Coarse-grain modelling of protein–protein interactions

Coarse-grain modelling of protein-protein interactions.

Here, we review recent advances towards the modelling of protein-protein interactions (PPI) at the coarse-grained (CG) level, a technique that is now widely used to understand protein affinity, aggregation and self-assembly behaviour. PPI models of soluble proteins and membrane proteins are separately described, but we note the parallel development that is present in both research fields with t...

Interactions of membranes with coarse-grain proteins : a comparison

We study the interactions between lipid bilayers and rigid transmembrane proteins by Monte Carlo simulations of generic coarse-grain models. Different popular protein models are considered and compared with each other, and key parameters such as the hydrophobicity and the hydrophobic mismatch are varied systematically. Furthermore, the properties of the membrane are manipulated by applying diff...

Coarse Grain Reconfigurable Architectures

The paper gives a brief survey over a decade of R&D on coarse grain reconfigurable hardware and related compilation techniques and points out its significance to the emerging discipline of reconfigurable computing.

Coarse-grain Coherence Tracking

Detection of Coarse- grain Parallelism

While the chip multiprocessor (CMP) has quickly become the predominant processor architecture, its continuing success largely depends on the parallelizability of complex programs. In the early 1990s great successes were obtained to extract parallelism from the inner loops of scientific computations. In this paper we show that significant amounts of coarse-grain parallelism exists in the outer p...